Cover for Caloric Restriction

Caloric Restriction

A Key to Understanding and Modulating Aging

A volume in Research Profiles in Aging

Book2002

Author:

Edward J. Masoro

Caloric Restriction

A Key to Understanding and Modulating Aging

A volume in Research Profiles in Aging

Book2002

 

Cover for Caloric Restriction

Author:

Edward J. Masoro

About the book

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Book description

For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages. Wh ... read full description

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  2. Book chapterAbstract only

    Chapter 1 - Overview

    Pages 1-10

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    Chapter 2 - Mortality characteristics

    Pages 11-19

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    Chapter 3 - Molecular and cellular biology

    Pages 21-49

  5. Book chapterAbstract only

    Chapter 4 - Organismic physiology

    Pages 51-91

  6. Book chapterAbstract only

    Chapter 5 - Age-associated diseases

    Pages 93-114

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    Chapter 6 - Mechanisms of the anti-aging action of caloric restriction

    Pages 115-156

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    Chapter 7 - Evolution of the anti-aging action of caloric restriction

    Pages 157-164

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    Chapter 8 - Caloric restriction mimetics

    Pages 165-178

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    Index

    Pages 179-183

About the book

Description

For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages.

What is the reason for this change in the usual pattern of aging? The evidence is overwhelming that the life extension results from a slowing of aging processes. And the factor responsible is the decrease in caloric intake. The obvious question: How does this factor work? A good question - and the reason that research on the anti-aging action of caloric restriction is today one of the most studied research areas in biological gerontology. For it is felt that if the biological mechanisms of the anti-aging action of caloric restriction can be uncovered, we would gain an understanding of the basic nature of aging processes, which would, in turn, yield possible interventions in human aging. This book aims to provide the growing number of researchers in this field (faculty, postdoctoral trainees, and graduate students) with a detailed knowledge of what is known about caloric restriction within the frame of gerontology, as well as insights on future of this field.

For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages.

What is the reason for this change in the usual pattern of aging? The evidence is overwhelming that the life extension results from a slowing of aging processes. And the factor responsible is the decrease in caloric intake. The obvious question: How does this factor work? A good question - and the reason that research on the anti-aging action of caloric restriction is today one of the most studied research areas in biological gerontology. For it is felt that if the biological mechanisms of the anti-aging action of caloric restriction can be uncovered, we would gain an understanding of the basic nature of aging processes, which would, in turn, yield possible interventions in human aging. This book aims to provide the growing number of researchers in this field (faculty, postdoctoral trainees, and graduate students) with a detailed knowledge of what is known about caloric restriction within the frame of gerontology, as well as insights on future of this field.

Details

ISBN

978-0-444-51162-1

Language

English

Published

2002

Copyright

Copyright © 2002 Elsevier B.V. All rights reserved

Imprint

Elsevier Science

Authors

Edward J. Masoro

Charleston, South Carolina USA