Cover for Cancer and Autoimmunity

Cancer and Autoimmunity

Book2000

Edited by:

Yehuda Shoenfeld and Eric M. Gershwin

Cancer and Autoimmunity

Book2000

 

Cover for Cancer and Autoimmunity

Edited by:

Yehuda Shoenfeld and Eric M. Gershwin

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Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical dis ... read full description

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  2. Book chapterFull text access

    Chapter 1 - Introduction: The Immune System, the Autoimmune State and Autoimmune Disease

    Jacob George and Yehuda Shoenfeld

    Pages 1-15

  3. Book chapterFull text access

    Subject Index

    Pages 437-446

About the book

Description

Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike.

The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival.

This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art.

This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.

Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike.

The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer in vivo, possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival.

This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art.

This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology.

Details

ISBN

978-0-444-50331-2

Language

English

Published

2000

Copyright

Copyright © 2000 Elsevier B.V. All rights reserved

Imprint

Elsevier Science

Editors

Yehuda Shoenfeld

Prof., M.D., Department of Medicine ‘B’ Research Unit of Autoimmune Diseases Chaim Sheba Medical Center (Affiliated to Tel-Aviv University) Tel-Hashomer 52621 Israel

Eric M. Gershwin

Prof., M.D., Division of Rheumatology/Allergy and Clinical Immunology University of California at Davis TB 192, School of Medicine Davis, CA 95616-8660 USA