Cover for Lahita's Systemic Lupus Erythematosus

Lahita's Systemic Lupus Erythematosus

Book • Sixth Edition2021

Edited by:

Robert G. Lahita, Karen H. Costenbader, ... Munther A. Khamashta

Lahita's Systemic Lupus Erythematosus

Book • Sixth Edition2021

 

Cover for Lahita's Systemic Lupus Erythematosus

Edited by:

Robert G. Lahita, Karen H. Costenbader, ... Munther A. Khamashta

About the book

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Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, whi ... read full description

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    Index

    Pages 683-698

About the book

Description

Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission.

Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness.

To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients.

A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries.

Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission.

Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness.

To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients.

A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries.

Key Features

  • Completely updated, revised, and expanded with the most comprehensive and accessible reference on SLE for clinicians and scientists
  • Full-color presentation throughout the book
  • Provides the latest information available on diagnosis and treatment
  • Incorporates an international panel of authors who are experts in their fields, with an emphasis on young, cutting-edge scientists and physicians
  • Completely updated, revised, and expanded with the most comprehensive and accessible reference on SLE for clinicians and scientists
  • Full-color presentation throughout the book
  • Provides the latest information available on diagnosis and treatment
  • Incorporates an international panel of authors who are experts in their fields, with an emphasis on young, cutting-edge scientists and physicians

Details

ISBN

978-0-12-820583-9

Language

English

Published

2021

Copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Imprint

Academic Press

Editors

Robert G. Lahita

Director of the institute for Autoimmune and Rheumatic Diseases at St. Joseph Health and Professor at Hackensack Meridian School of Medicine, United States

Karen H. Costenbader

Professor of Medicine, Harvard Medical School, Boston, MA, United States

Richard Bucala

Rheumatology, Professor of Medicine, Pathology, and Epidemiology & Public Health, Program in Human Translational Immunology, Yale University School of Medicine, New Haven, CT, United States

Susan Manzi

Medicine Institute, Allegheny Health Network, Pittsburgh, PA, United States

Professor of Medicine, Temple University, Philadelphia, PA, United States

Munther A. Khamashta

Lupus Clinic, Rheumatology, Dubai Hospital, Dubai, United Arab Emirates