Cover for Cancer Genomics

Cancer Genomics

From Bench to Personalized Medicine

Book2014

Edited by:

Graham Dellaire, Jason. N. Berman and Robert J. Arceci

Cancer Genomics

From Bench to Personalized Medicine

Book2014

 

Cover for Cancer Genomics

Edited by:

Graham Dellaire, Jason. N. Berman and Robert J. Arceci

About the book

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Book description

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the pa ... read full description

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  2. Book chapterNo access

    Abbreviations

    Pages 467-471

  3. Book chapterNo access

    Glossary

    Pages 473-486

  4. Book chapterNo access

    Index

    Pages 487-494

About the book

Description

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment.

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment.

Key Features

  • Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics.
  • Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.
  • Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics.
  • Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.

Details

ISBN

978-0-12-396967-5

Language

English

Published

2014

Copyright

Copyright © 2014 Elsevier Inc. All rights reserved.

Imprint

Academic Press

Editors

Graham Dellaire

Departments of Pathology and Biochemistry & Molecular Biology Dalhousie University, Halifax, Canada

Jason. N. Berman

IWK Health Centre, Departments of Pediatrics, Pathology and Microbiology and Immunology, Dalhousie University, Halifax, Canada

Robert J. Arceci

The Ron Matricaria Institute of Molecular Medicine at Phoenix Childrens Hospital, Department of Child Health, University of Arizona, College of Medicine, Phoenix, USA