Cover for Calmodulin Antagonists and Cellular Physiology

Calmodulin Antagonists and Cellular Physiology

Book1985

Edited by:

HIROYOSHI HIDAKA and DAVID J. HARTSHORNE

Calmodulin Antagonists and Cellular Physiology

Book1985

 

Cover for Calmodulin Antagonists and Cellular Physiology

Edited by:

HIROYOSHI HIDAKA and DAVID J. HARTSHORNE

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Calmodulin Antagonists and Cellular Physiology focuses on the biochemistry of calmodulin antagonists as regulators of cellular physiology. Emphasis is placed on the use of calmodul ... read full description

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    Index

    Pages 531-543

About the book

Description

Calmodulin Antagonists and Cellular Physiology focuses on the biochemistry of calmodulin antagonists as regulators of cellular physiology. Emphasis is placed on the use of calmodulin antagonists as an indicator of calmodulin function. The mechanism of action of calmodulin antagonists and their interactions with calmodulin are explored. This book is comprised of 33 chapters and begins with an introduction to the biochemical aspects of calmodulin as well as its distribution and functions, followed by a discussion on how calmodulin antagonists and other agents modulate Ca2+-dependent regulatory systems. The next section is devoted to the mechanism of action of calmodulin antagonists and includes chapters that examine the interaction of various drugs with calmodulin and the structure-activity relationships of calmodulin antagonists. The effects of calmodulin antagonists on cell proliferation and growth are then discussed. The remaining chapters deal with the role of calmodulin antagonists in cell function and the contractile process, along with their effect on protein kinase C. This monograph will be a useful resource for biochemists as well as students and researchers in biochemistry.

Calmodulin Antagonists and Cellular Physiology focuses on the biochemistry of calmodulin antagonists as regulators of cellular physiology. Emphasis is placed on the use of calmodulin antagonists as an indicator of calmodulin function. The mechanism of action of calmodulin antagonists and their interactions with calmodulin are explored. This book is comprised of 33 chapters and begins with an introduction to the biochemical aspects of calmodulin as well as its distribution and functions, followed by a discussion on how calmodulin antagonists and other agents modulate Ca2+-dependent regulatory systems. The next section is devoted to the mechanism of action of calmodulin antagonists and includes chapters that examine the interaction of various drugs with calmodulin and the structure-activity relationships of calmodulin antagonists. The effects of calmodulin antagonists on cell proliferation and growth are then discussed. The remaining chapters deal with the role of calmodulin antagonists in cell function and the contractile process, along with their effect on protein kinase C. This monograph will be a useful resource for biochemists as well as students and researchers in biochemistry.

Details

ISBN

978-0-12-347230-4

Language

English

Published

1985

Copyright

Copyright © 1985 Elsevier Inc. All rights reserved.

Imprint

Academic Press

Editors

HIROYOSHI HIDAKA

Department of Pharmacology, Mie University, School of Medicine, Edobashi, Tsu, Japan

DAVID J. HARTSHORNE

Department of Nutrition and Food Science, University of Arizona, Tucson, Arizona